3 syllables: Thi, a, mine. Stress on Thi.
THEYE-uh-meen
/ˈθaɪəˌmiːn/
Thiamine is pronounced THEYE-uh-meen (/ˈθaɪəˌmiːn/). It has three syllables (Thi-a-mine), with the stress on "Thi". As a noun, a water-soluble vitamin (B1) essential for carbohydrate metabolism and neural function. Thiamine acts as a coenzyme in energy-producing pathways and supports nerve health; a deficiency can lead to beriberi or Wernicke–Korsakoff syndrome. It is commonly consumed in fortified foods and supplements.
nounA water-soluble vitamin (B1) essential for carbohydrate metabolism and neural function. Thiamine acts as a coenzyme in energy-producing pathways and supports nerve health; a deficiency can lead to beriberi or Wernicke–Korsakoff syndrome. It is commonly consumed in fortified foods and supplements.
- You may default to saying 'thee-uh-meen' with /iː/ mispronounced; correct by isolating /miːn/ and ensuring the consonants are clear. - Mistaking /θ/ for /t/ or /d/ at the start; keep interdental fricative with tongue to the upper teeth. - Misplacing stress as on the first syllable; mark the second syllable as stressed: thi-a-MINE. - Over-reducing the middle /ə/ so the word sounds like two syllables; practice keeping the /ə/ quick but audible and connect to /ˈmiːn/.
"The patient’s thiamine level was checked before prescribing glucose infusions."
"Thiamine is often given alongside other B vitamins in a multivitamin."
"Chronic alcohol use can impair thiamine absorption and lead to deficiency."
US: /ˌθaɪ.əˈmiːn/; UK: /ˌθaɪ.əˈmiːn/; AU: /ˌθaɪ.əˈmiːn/. Start with the initial voiceless interdental /θ/, then /aɪ/ as in time, a schwa-like /ə/ in the middle, and the final /miːn/ with a long E. Primary stress on the second syllable: thi-a-MINE. For audio reference, listen to medical pronunciation demos on Pronounce or Forvo.
Common errors: (1) Pronouncing as 'thee-am-ine' with a hard /d/ or /th/ variations; (2) Misplacing stress as on the first syllable; (3) Splitting the /miːn/ into a short /min/ or /meen/ without length. Correction: keep /θaɪ.əˈmiːn/ with the /θ/ voiceless dental fricative, the /aɪ/ diphthong, a reduced /ə/ in the middle, and the final long /iːn/. Practice slowly: /θ/ + /aɪ/ + /ə/ + /ˈmiːn/ and then speed up.
US/UK/AU share /ˌθaɪ.əˈmiːn/ with main differences in vowel quality; US and UK usually have /ˈmiːn/ with a clear long /iː/; AU tends to a slightly flatter /iː/ and less rhoticity doesn’t apply here since thiamine is not a rhotic word. In all variants the primary stress is on the second syllable. Mouth posture is similar; ensure the initial /θ/ is voiceless and produced with tongue-tip close to the upper teeth.
The difficulty lies in the initial /θ/ sound and the /ˌθaɪ.ə/ sequence, which can blur in rapid speech, and in maintaining the long /iː/ at the end after a reduced middle vowel. People often insert a /d/ or shorten /ˈmiːn/. Focus on keeping the interdental fricative /θ/, the diphthong /aɪ/, the schwa /ə/, and the final /ˈmiːn/ intact in sequence.
A distinctive feature is the clear transition from the front-dominant /θ/ to the high front /iː/ in the final syllable, a combination that requires precise tongue position to prevent blending into /f/ or /v/ sounds. Emphasize the two halves: /θaɪ.ə/ then /ˈmiːn/. This is a word where stress naturally rises on the last syllable, which helps with fluent clinical or academic speech.
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- US: maintain clear /ˈmiːn/, keep stress on the final syllable; practice with longer vowels and a slightly harder /θ/ at the start. - UK: similar to US; mid vowels may be a touch more schwa-like; ensure the /θ/ is precise to differentiate from /t/. - AU: often more relaxed vowel length; aim to keep the final /iːn/ brisk and distinct from /ɪn/; use strong aspiration on /θ/ to avoid blending with /s/ or /f/.
Thiamine derives from the combination of thio- (sulfur-containing) and amino- (nitrogen-containing) components, reflecting the molecule’s thiazole ring and amino alcohol structure. The term thiamine was coined in the early 20th century as biochemists identified its role as a precursor to thiamine pyrophosphate, a key coenzyme. It originates from the Greek ti(s) + amine, with “thio-” indicating sulfur substitution, and the suffix -ine common to vitamins. First isolated in the 1930s during research into beriberi, thiamine’s recognition as an essential B vitamin followed rapid advances in nutrition science, fortification efforts, and therapeutic supplementation. The modern spelling “thiamine” is now standard in medical literature, though you may encounter “thiamin” in some older texts and pharmacology references. The word’s development mirrors broader vitamin taxonomy, shifting from functional descriptions to standardized nomenclature while reinforcing its role as a vital nutrient for energy metabolism and nerve function.
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Words that rhyme with "Thiamine"
-ain sounds
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