3 syllables: Tra, zo, done. Stress on Tra.
TRAZ-uh-dohn
/ˈtræzəˌdoʊn/
Trazodone is pronounced TRAZ-uh-dohn (/ˈtræzəˌdoʊn/). It has three syllables (Tra-zo-done), with the stress on "Tra". Trazodone is a prescription antidepressant and sedative used to treat major depressive disorder and insomnia by modulating serotonin pathways. The term denotes a chemical compound whose pronunciation is commonly encountered in clinical and pharmacological contexts. It is a multi-syllabic word that benefits from careful emphasis and vowel clarity when spoken in medical or patient-facing discussions.
nounTrazodone is a prescription antidepressant and sedative used to treat major depressive disorder and insomnia by modulating serotonin pathways. The term denotes a chemical compound whose pronunciation is commonly encountered in clinical and pharmacological contexts. It is a multi-syllabic word that benefits from careful emphasis and vowel clarity when spoken in medical or patient-facing discussions.
"The doctor prescribed trazodone to help with sleep disturbances associated with depression."
"During the clinic visit, she asked how trazodone might interact with her current medications."
"He reported that trazodone helped him fall asleep more quickly, though it caused some daytime grogginess."
Trazodone is pronounced tra-ZOH-done, with primary stress on the second syllable. IPA: US: træˈzoʊˌdiːn. Focus on the long o in the second syllable and a clear 'z' sound between the first and second syllables. You’ll hear a slight secondary emphasis on the final syllable in rapid speech. If you’re teaching it aloud, exaggerate the second syllable briefly to help learners lock the rhythm.
Common errors include reducing the second syllable to a quick ‘zo’ or misplacing the primary stress on the first syllable (TRA-zo-done). Another frequent issue is pronouncing the second syllable with a short o like ‘dot’ instead of a long /oʊ/ as in ‘go.’ Corrective tips: emphasize -zo- with a clear long o: tra-ZOH-done, prolong the /oʊ/ slightly, and keep the final ‘done’ as /diːn/ rather than /dn/.
US: traˈzoʊˌdiːn, with a clear /oʊ/ in the second syllable and a final /iːn/. UK: træˈzɒdəʊn or træˈzɒdɒn, with a shorter first vowel and a more clipped final /ən/ or /n/ depending on speaker. AU: similar to UK, but possible slight vowel flattening and non-rhoticity effects that may reduce the rhotic quality of final vowels. In all: keep the /z/ sonorant crisp and the second syllable long, adjust vowel quality by dialect-specific shifts, and maintain the final nasal closure.
The difficulty comes from the multi-syllabic structure and the long, stressed second syllable with a precise /oʊ/ diphthong. Non-native speakers often misplace the stress or shorten the /oʊ/ to /ɒ/ or /ɔ/. Also, the initial consonant cluster /tr/ can be challenging if you aren’t fluent with tr- onset words. Practice by isolating tra- and -zo- segments, then blend at a comfortable pace, focusing on the long /oʊ/ and the final /diːn/.
The -done suffix is pronounced like /diːn/ and often blends with the preceding vowel; remember it as don+e with a long e sound. A memory trick: think of the drug’s role in calming sleep, so link the “-zone” sound to a relaxed breath on the long /oʊ/ followed by a soft /diːn/. Rehearse with patient-provided contexts to fix the cadence, e.g., ‘I was prescribed trazodone for sleep.’
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Trazodone derives from the chemical naming conventions of synthetic antidepressants, combining a morpholine-derived group with a triazolopyridine moiety. The prefix trazo- likely reflects the carousel of fragments used in medicinal chemistry to indicate a triazolo- structure, while -done is a common suffix in pharmaceutical naming often linked to chemical derivatives. The word entered medical literature in the mid-to-late 20th century as trazodone was developed in the wake of SSRI and heterocyclic antidepressant research. Its first known uses appeared in pharmacology journals as researchers described pharmacokinetics, metabolism, and clinical trials. Over time, trazodone has become a standard term in prescribing information, patient education materials, and clinical discussions, maintaining a phonetic consistency that aligns with other drug names from Greek and Latin word formation influencing pharmaceutical nomenclature.
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💡 These words have similar meanings to "Trazodone" and can often be used interchangeably.
🔄 These words have opposite meanings to "Trazodone" and show contrast in usage.
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Words that rhyme with "Trazodone"
-don sounds
Practice with these rhyming pairs to improve your pronunciation consistency:
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