3 syllables: Sy, phi, lis. Stress on Sy.
SIF-uh-lis
/ˈsɪfəlɪs/
Syphilis is pronounced SIF-uh-lis (/ˈsɪfəlɪs/). It has three syllables (Sy-phi-lis), with the stress on "Sy". Syphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It typically progresses through stages (primary, secondary, latent, and tertiary) if untreated, with distinct clinical manifestations in each stage. The term is widely used in medical, public health, and research contexts and is pronounced with careful attention to syllable stress and vowel quality due to its multi-syllabic, foreign-origin name.
nounSyphilis is a sexually transmitted infection caused by the bacterium Treponema pallidum. It typically progresses through stages (primary, secondary, latent, and tertiary) if untreated, with distinct clinical manifestations in each stage. The term is widely used in medical, public health, and research contexts and is pronounced with careful attention to syllable stress and vowel quality due to its multi-syllabic, foreign-origin name.
"The patient was diagnosed with syphilis after a routine blood test."
"Public health officials monitor syphilis trends to prevent outbreaks."
"The physician explained the stages of syphilis and the importance of treatment."
Pronounce as /ˈsɪfəlɪs/ (SIF-uh-lis). The primary stress falls on the first syllable. Start with the 'sih' sound /sɪ/ followed by a light 'f' /f/, then a short schwa-like /ə/ in the second syllable, and finish with /lɪs/. Tip: keep the vowels lax and the final consonant crisp. You can listen to clinical pronunciations on medical diction resources or Forvo for native speaker examples.
Common mistakes include saying /ˈsaɪfəlɪs/ with a diphthong in the first syllable or misplacing the stress on the second syllable. Another error is prolonging the second syllable or turning the final /s/ into /z/. To correct: use /ˈsɪfəlɪs/ with a short /ɪ/ in the first syllable, a clear /f/ followed by a neutral /ə/ and a crisp final /lɪs/. Practice with minimal pairs focusing on the /ɪ/ vs /aɪ/ and keeping the /s/ voiceless.
US/UK/AU share the /ˈsɪfəlɪs/ skeleton, but vowel quality shifts subtly. In US English, /ɪ/ can be a lax short i as in 'bit'; UK English often has a more clipped /ɪ/ with slightly shorter vowels; Australian English tends toward a more centralized vowel in the second syllable, but the final /ɪs/ remains light. The main difference is vowel quality of /ɪ/ and the overall vowel reduction in American speech. The stress remains on the first syllable in all three.
The difficulty lies in the short, reduced second syllable and the initial consonant cluster /sf/. Phonemes require precise production: a compact /s/ followed by a voiceless /f/ without an audible break, and a quick /ə/ before /l/ and /s/. Non-native speakers may misplace stress or elongate the second syllable. Focus on keeping the first syllable stressed, with a tight /f/ and a light, unstressed second syllable.
A distinctive feature is the 'sy' cluster starting with /s/ then /ɪ/; many speakers misread it as /saɪ/ like 'sigh'. The correct onset blends /s/ and /ɪ/ as a crisp, short vowel, yielding /ˈsɪ/ rather than /ˈsaɪ/. The second syllable carries a short /ə/ before the /lɪs/; the 'l' is light and the final /s/ is voiceless. This combination—beginning with /sɪ/ and ending with /lɪs/—is the anchor of proper pronunciation.
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Syphilis derives from Renaissance Latin syphilis, or Latinized Italian cipilis, from the name of a 16th-century poem describing a shepherd named Syphilus who was punished by the gods with this disease. The term came into medical usage in the 16th century through Giovanni da Vigo and other physicians, replacing older terms like lues and the venereal disease label. The root has uncertain immediate origin but is often linked to a poem's name rather than a descriptive medical term. Over centuries, the word shifted from a literary label to a formal medical diagnosis, and modern usage retains a classical-sounding clinical cadence. The pronunciation embodies a trochaic-tetrameter feel in English, with a stress pattern that guides correct vowel articulation and consonant timing. The 'sy' cluster historically elicited variable pronunciations in early English, but contemporary standard usage is stable across major dialects, reflecting broader standardization in medical terminology. Today, syphilis is almost exclusively tied to Treponema pallidum as the causative agent, and the term functions within epidemiology, clinical medicine, and public health surveillance.
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💡 These words have similar meanings to "Syphilis" and can often be used interchangeably.
🔄 These words have opposite meanings to "Syphilis" and show contrast in usage.
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Words that rhyme with "Syphilis"
-lis sounds
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