2 syllables: Synth, roid. Stress on Synth.
SIN-throyd
/ˈsɪnθɹɔɪd/
Synthroid is pronounced SIN-throyd (/ˈsɪnθɹɔɪd/). It has two syllables (Synth-roid), with the stress on "Synth". Synthroid is a synthetic form of thyroxine (T4) used to treat thyroid hormone deficiency. It is a brand-name medication, commonly prescribed for hypothyroidism, and works by replacing or supplementing natural thyroid hormones. In everyday speech, it is referred to as a specific drug name rather than a common noun.
nounSynthroid is a synthetic form of thyroxine (T4) used to treat thyroid hormone deficiency. It is a brand-name medication, commonly prescribed for hypothyroidism, and works by replacing or supplementing natural thyroid hormones. In everyday speech, it is referred to as a specific drug name rather than a common noun.
"The doctor prescribed Synthroid to manage her thyroid levels."
"She started taking Synthroid a week ago and is monitoring any side effects."
"Pharmacists should verify the patient’s dosage when dispensing Synthroid."
Pronounce it as SINGK-throyd? Actually: /ˈsɪnθˌrɔɪd/. The first syllable is stressed: SIN-, with a short i as in 'sit'. The second syllable is /θ/ (the 'th' as in 'think'), followed by /rɔɪd/ where 'roid' rhymes with 'avoid' (oyd). Put it together: SINTH-ROYD, with a light pause between syllables, ending in a rounded, blue-sounding /ɔɪd/. Pay attention to the 'th' as voiceless dental fricative and ensure the 'roid' sounds like 'roid' in 'avoid'.
Common errors: treating 'synth' as 'sin-th' with a soft 'th' as in 'the' (voiced) instead of the voiceless /θ/; mispronouncing 'roid' as 'royd' with a long 'o' instead of /ɔɪ/; stressing the second syllable instead of the first. Correction: say /ˈsɪnθˌrɔɪd/ with a clear voiceless /θ/ in the first word, lunar 'r' sound, and the long 'oy' diphthong in the second, ending with a crisp /d/.
Across US/UK/AU accents, the core sounds stay the same: /ˈsɪnθˌrɔɪd/. The rhotics may vary: US and AU typically pronounced with a rhotic /ɹ/; UK may be non-rhotic in some speakers but medical terms often preserve /r/ in careful speech. The /ɔɪ/ diphthong in 'roid' is somewhat closer to 'oi' in 'oil' in all, but vowel quality may be slightly tenser in US pronunciation. IPA remains /ˈsɪnθˌrɔɪd/ for standard medical usage across regions.
Two main challenges: the initial 'th' /θ/ is a voiceless dental fricative uncommon in some languages; the second syllable /rɔɪd/ contains the /ɔɪ/ diphthong that can blend into a simple /ɔɪ/ or /oid/ for non-native speakers. The stress pattern is strong on the first syllable, so you must keep /ˈsɪnθ/ prominent before the /rɔɪd/. Practice by isolating the 'th' and the 'oy' sound separately before blending.
Unique to medical contexts is maintaining a precise /θ/ sound and the sharp, clipped onset of the first syllable 'SIN-'. You’ll want to separate the syllables clearly in patient education: /ˈsɪnθ/ + /ˌrɔɪd/. A common quirk is relaxing the 'th' and merging into 'sinyroid' when hurried; avoid that by practicing with a tongue-tip placement behind the upper front teeth, then release air for the /θ/.
🗣️ Voice search tip: These questions are optimized for voice search. Try asking your voice assistant any of these questions about "Synthroid"!
US: rhotic /ɹ/ with a slight backward tongue posture; UK: often non-rhotic in careful speech but medical terms keep the /ɹ/; AU: rhotic, with a slightly broader vowel in /ɔɪ/. The /θ/ remains a voiceless dental fricative in all. Vowel quality: /ɪ/ in the first syllable is a near-close near-front vowel; /ɔɪ/ in 'roid' is a mid-to-high diphthong toward /ɪ/. Practice IPA-aligned mouth positions for each variety.
Synthroid is a branded pharmaceutical name. It derives from a combination of 'synthetic' and a familiar pharmaceutical suffix that signals a synthetic drug product, with the 'roid' ending common in steroids and related medications. The term encapsulates its purpose: a synthetic thyroid hormone replacement. While 'thyroid' is the organ of action, 'Synthroid' conveys a trademarked product designed to mimic the body’s natural thyroid hormone T4. First introduced in the late 20th century as a standardized treatment for hypothyroidism, Synthroid quickly became a common reference in medical and patient communications. The exact origin of the brand name involves pharmaceutical branding strategies, combining recognizable medical roots with a simple, memorable phonetic form. Over time, clinicians and patients came to treat Synthroid as shorthand for the generic levothyroxine when discussing prescription options and therapy monitoring.
💡 Etymology tip: Understanding word origins can help you remember pronunciation patterns and recognize related words in the same language family.
Help others use "Synthroid" correctly by contributing grammar tips, common mistakes, and context guidance.
💡 These words have similar meanings to "Synthroid" and can often be used interchangeably.
🔄 These words have opposite meanings to "Synthroid" and show contrast in usage.
📚 Vocabulary tip: Learning synonyms and antonyms helps you understand nuanced differences in meaning and improves your word choice in speaking and writing.
Words that rhyme with "Synthroid"
-oid sounds
Practice with these rhyming pairs to improve your pronunciation consistency:
🎵 Rhyme tip: Practicing with rhyming words helps you master similar sound patterns and improves your overall pronunciation accuracy.
