7 syllables: Ox, a, zo, li, di, no, ne. Stress on li.
ahk-suh-zoh-LID-in-ohn
/ɑks ə zoʊ ˈlɪdɪnoʊn/
Oxazolidinone is pronounced ahk-suh-zoh-LID-in-ohn (/ɑks ə zoʊ ˈlɪdɪnoʊn/). It has seven syllables (Ox-a-zo-li-di-no-ne), with the stress on "li". Oxazolidinone is a class of synthetic antibiotics containing a 5-membered oxazolidinone ring fused to other chemical groups. It denotes a specific chemical class used in medicine, notable for inhibition of bacterial protein synthesis. The term is used in pharmacology, chemistry, and medical literature with precise structural connotations.
nounOxazolidinone is a class of synthetic antibiotics containing a 5-membered oxazolidinone ring fused to other chemical groups. It denotes a specific chemical class used in medicine, notable for inhibition of bacterial protein synthesis. The term is used in pharmacology, chemistry, and medical literature with precise structural connotations.
"The researcher cited oxazolidinone derivatives when discussing novel antimicrobial agents."
"Oxazolidinone antibiotics like linezolid are reserved for resistant infections."
"The synthesis of an oxazolidinone core requires careful control of stereochemistry."
Break it as ox-a-zi-li-di-no-ne. Primary stress typically falls near the second-to-last main syllable: ox-aza-li-DI-no-ne, depending on the speaker. IPA: US ˌɒkˌzæ.zəˈlɪ.dɪˌnoʊn; UK ˌɒk.zəˈzɪl.ɪ.dɪˈnəʊn; AU ˌɒk.zəˈzɪ.dɪ.nəʊn. Focus on the sequence of syllables and keep the consonants distinct (z, l, d, n).
Common errors: flattening the mid syllables into a single schwa run, misplacing stress on the wrong syllable, and merging -di- with -no- leading to oxazolidinon- instead of -dɪˈnoʊn. Correction: segment the word and practice each cluster: /ˌɒkˌzæ.zəˈlɪ.dɪˌnoʊn/; keep /dɪ/ clearly as a separate syllable and maintain a light but present final /noʊn/. Practice with slow tempo, then speed up while preserving syllable boundaries.
US: rhotic, tends to articulate the r-colored a bit and maintain /ɒ/ or /ɑ/ depending on speaker; UK tends to shorter /ɒ/ with less rhoticity in non-rhotic speakers; AU often shows relaxed vowel quality, with slightly broader /oʊ/ → /oʊn/ at the end. Ensure final -one is clear /ˌoʊn/ in all accents. IPA references: US ˌɒkˌzæ.zəˈlɪ.dɪˌnoʊn; UK ˌɒk.zəˈzɪl.ɪ.dɪˈnəʊn; AU ˌɒk.zəˈzɪ.dɪ.nəʊn.
Because it contains multiple adjacent consonants and a five-membered heterocycle name, with three internal vowels and the sequence -z- a- -li- -di- -no- -ne. The consonant cluster /z/ followed by /ə/ and /l/ can blur in rapid speech, and the final /noʊn/ may be inhaled or devoiced. Practice by isolating syllables, emphasizing /z/ and /d/ clarity, and linking /noʊn/ as a solid, stressed unit.
The word features a rare sequence -zə- followed by -lɪ-, so ensure you don’t merge the z with the following l and eɪ-like vowel sound. The middle 'di' is short but distinct; avoid blending /dɪ/ with adjacent vowels. Maintain clear articulation through the transitions: /zəˈlɪ.dɪ/. Understanding these micro-transition points helps you prevent mispronunciations that resemble other heterocyclic terms.
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Oxazolidinone originates from combining the heterocyclic ring name oxazolidine (oxazo- + -lidin- forming a 5-membered ring containing oxygen and nitrogen) with the -one suffix denoting a ketone-like functional group in chemistry. The prefix 'oxazolidin-' signals the presence of an oxazolidine backbone within the overall molecule, and the final '-one' indicates a carbonyl-containing functional group integrated into the ring system. The term entered scientific use in the 1960s–1970s amid rapid growth in synthetic antibiotics and heterocyclic chemistry, with first formal usage appearing in chemical literature describing novel heterocyclic compounds containing an oxazolidinone ring. The name was systematically adopted in pharmacology to categorize drugs whose core ring structure includes the oxazolidinone motif, later becoming central to antibiotic classes such as linezolid and tedizolid. Over time, the word has grown to denote a broad class rather than a single compound, while still referring to molecules that possess the characteristic oxazolidinone ring and associated bioactivity. First known use is documented in mid-20th century chemical nomenclature, aligning with the era’s emphasis on heterocyclic rings in medicinal chemistry.
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Words that rhyme with "Oxazolidinone"
-ine sounds
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