4 syllables: My, o, glo, bin. Stress on glo.
meye-uh-GLOH-bin
/ˌmaɪəˈɡloʊbɪn/
Myoglobin is pronounced meye-uh-GLOH-bin (/ˌmaɪəˈɡloʊbɪn/). It has four syllables (My-o-glo-bin), with the stress on "glo". Myoglobin is a globular heme-containing protein responsible for oxygen storage and transport within muscle tissue. A compact, highly concentrated molecule, it binds oxygen at low concentrations and releases it during muscle activity. It plays a key role in sustaining aerobic metabolism in muscle fibers, particularly during steady, prolonged exertion.
nounMyoglobin is a globular heme-containing protein responsible for oxygen storage and transport within muscle tissue. A compact, highly concentrated molecule, it binds oxygen at low concentrations and releases it during muscle activity. It plays a key role in sustaining aerobic metabolism in muscle fibers, particularly during steady, prolonged exertion.
"The researchers measured myoglobin levels to assess muscle damage after intense exercise."
"In biochemistry, myoglobin's structure helps explain its strong affinity for oxygen."
"Certain athletes monitor myoglobin to understand their muscle oxygenation under load."
Pronounce as maɪˈoʊɡloʊbɪn for US; in the UK it’s maɪəˈɡləʊbɪn and in Australia maɪəˈɡləːbɪn. The primary stress falls on the second syllable: my-O-glo-bin. Start with /maɪ/ (like 'my'), then a clear /ˈoʊ/ or /əʊ/ diphthong before /ɡloʊ/ or /ɡləʊ/, and finish with /bɪn/ or /bɪn/. Mouth posture: lips relaxed, tongue high for /aɪ/ and /ɪ/; back of tongue rises for /ɡl/ cluster. Audio references: consult pronunciation resources to hear the three variants.
Common mistakes include misplacing stress (saying myo-ˈglobin) and mispronouncing the middle vowel as /ɪ/ or /iː/. Some learners flatten the second syllable to /gloʊ/ without the /loʊ/ emphasis, or mix the velar /g/ with a /dʒ/ sound. Correct by emphasizing the second syllable with /ˈɡloʊ/ and ensuring the final syllable is /bɪn/ rather than /bin/. Practice with minimal pairs to fix the vowel quality and syllable timing.
In US you have maɪˈoʊɡloʊbɪn with a strong /oʊ/ in the second syllable. UK tends to a more centralized vowel in the second syllable: maɪəˈɡləʊbɪn, with a lengthened /ə/ and a clear /əʊ/ in the final part. Australia often mirrors UK vowel qualities but with a slightly flatter /ə/ in the second syllable and a broad /ɪ/ at the end: maɪəˈɡləːbɪn. In all cases keep the stress on the second syllable and the final /ɪn/ stem distinct.
The difficulty lies in the multi-syllabic structure and the two consecutive consonant clusters: /ɡl/ in the middle and the final /bɪn/. Learners often misplace the /oʊ/ vowel, producing /ˈmaɪoʊɡlɒbɪn/ or /ˈmaɪɒɡlɪbɪn/. Focus on the glide /oʊ/ after /maɪ/ and keep the /ɡl/ cluster tight without inserting a vowel. Also ensure the /b/ links cleanly to /ɪn/ rather than making it /biːn/. Practice phoneme-by-phoneme to stabilize rhythm.
A distinctive feature is the diphthong transition in the second syllable: US /maɪˈoʊɡloʊbɪn/ uses a clear /oʊ/ across two syllables before the /ˈɡloʊ/ portion, whereas UK/AU reduce the /oʊ/ into /əʊ/ and gradually blend into /ɡləʊ/. This subtle vowel shift changes the overall resonance of the word, affecting perceived formality and ease of articulation. Listen for the rounded mouth shape on /oʊ/ and keep the syllables evenly timed.
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