4 syllables: Le, vo, do, pa. Stress on do.
lev-uh-DOH-puh
/lɛvəˈdoʊpə/
Levodopa is pronounced lev-uh-DOH-puh (/lɛvəˈdoʊpə/). It has four syllables (Le-vo-do-pa), with the stress on "do". Levodopa is a prescription medication used to treat Parkinson’s disease by replenishing brain dopamine. It is typically administered with carbidopa to improve efficacy and reduce side effects. The term combines the drug’s chemical name with the Greek-formed root to reflect its therapeutic purpose and origin in biochemistry.
nounLevodopa is a prescription medication used to treat Parkinson’s disease by replenishing brain dopamine. It is typically administered with carbidopa to improve efficacy and reduce side effects. The term combines the drug’s chemical name with the Greek-formed root to reflect its therapeutic purpose and origin in biochemistry.
"Levodopa is the standard first-line therapy for many patients with Parkinson’s disease."
"The patient was started on levodopa/carbidopa to manage motor symptoms."
"Researchers are studying long-acting formulations of levodopa to reduce dosing frequency."
Pronounce as le-vo-DO-pa with secondary stress on the first syllable. IPA (US): ˌliːvoʊˈdoʊpə. Place your tongue for L, then raise your mid back to produce the long eo diphthong in 'leo' and the long 'o' in 'do'. The stress falls on the third syllable: -do-. You’ll sound natural if you keep it fluid in clinical speech and avoid chunking into two equal halves. Audio reference: search Pronounce or YouGlish for 'levodopa' pronunciation examples.
Common errors: misplacing stress (putting emphasis on ‘leo’ or 'pa'); mispronouncing the central /doʊ/ as a short vowel; altering the final '-pa' into a plosive or reducing the syllables. Corrections: stress the third syllable: le-vo-DO-pa; ensure /doʊ/ is a clear long vowel, not a muted or clipped form; end with a soft 'ə' rather than a hard 'a'. Practice with slow, syllable-timed reading to preserve the multi-syllabic rhythm.
In US English, the primary stress is on the third syllable: ˌliːvoʊˈdoʊpə, with a clear long '-doʊ-'. UK/US both place emphasis on the same syllable, but vowel qualities shift: UK often uses a slightly shorter /oʊ/ and crisper /p/. Australian pronunciation tends to be closer to US but with subtle vowel reduction and a more rolled or flapped 'r' only if followed by a vowel; otherwise non-rhotic. Focus on the /oʊ/ diphthong and the final schwa.
Because it combines a non-native compound with a non-English root. Specifically, the third syllable features a long /oʊ/ sound in /doʊ/ and the final unstressed /ə/; many speakers misplace the primary stress earlier, yielding le-VO-do-pa or le-vo-DO-PA with inconsistent rhythm. Also, L-dopa’s spelling includes a fixed hyphen in medical usage; the sequence /vɒ/ or /voʊ/ can be mis-articulated by non-native speakers. IPA cues help anchor the correct vowels and rhythm.
There are no silent letters in standard pronunciation of levodopa; every syllable is voiced. The most prominent stress pattern is on the third syllable: le-vo-DO-pa. Pay attention to the long /doʊ/ and the final schwa /ə/. Some speakers may reduce the final vowel slightly depending on pace, but in careful speech, the final /ə/ remains audible. The word remains iambic-ish in natural medical cadence—a light, steady beat with a clear center stress.
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Levodopa derives from a blend of chemical nomenclature and biochemistry. The core molecule is L-dopa (L-3,4-dihydroxyphenylalanine), an amino acid derivative. The prefix ‘Levo-’ signals the levo- (left-handed) stereochemistry common to many chiral amino acids, while ‘-dopa’ traces to dopa, short for dopa-tyrosine derivatives involved in catecholamine synthesis. The term entered medical lexicon in the mid-20th century as researchers identified its potential to cross the blood–brain barrier and replenish brain dopamine. Early work by scientists exploring the treatment of Parkinsonian symptoms established L-dopa as the foundational therapy, with later combination formulations (e.g., levodopa with carbidopa) enhancing bioavailability and tolerability. The first documented uses in clinical literature appeared in the 1960s, rapidly becoming a cornerstone of movement disorder management. Over decades, pharmaceutical refinements have sought to optimize dosing, reduce fluctuations, and tailor regimens to disease progression and individual patient response.
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Words that rhyme with "Levodopa"
-opa sounds
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