3 syllables: Le, pro, sy. Stress on Le.
LEP-ruh-see
/ˈlɛpɹəsi/
Leprosy is pronounced LEP-ruh-see (/ˈlɛpɹəsi/). It has three syllables (Le-pro-sy), with the stress on "Le". Leprosy is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the skin, nerves, and mucous membranes. It progresses slowly and can lead to numbness and disfiguring lesions if untreated. The term is historically tied to social stigma, but medically it denotes a specific bacterial infection with well-established treatments.
nounLeprosy is a chronic infectious disease caused by Mycobacterium leprae, primarily affecting the skin, nerves, and mucous membranes. It progresses slowly and can lead to numbness and disfiguring lesions if untreated. The term is historically tied to social stigma, but medically it denotes a specific bacterial infection with well-established treatments.
"The doctor diagnosed the patient with leprosy and began multidrug therapy."
"Public health campaigns aim to reduce the stigma surrounding leprosy and encourage treatment."
"Historically, leprosy patients were isolated in leper colonies, though modern practice favors inclusive care."
Leprosy is pronounced /ləˈproʊzi/ in US English and /ləˈprəʊzi/ in UK and AU. The primary stress is on the second syllable: le-PRO-sy. Begin with a light, unstressed /lə/ (uh), then a strong /ˈproʊ/ (proh), ending with /zi/ as a clear 'zee.' Think: luh-PROH-zee. Audio resources can reinforce the exact mouth shapes, especially the /oʊ/ diphthong and the voiced /z/ at the end.
Common errors include misplacing the stress (saying le-PRO-sy or le-pró-sy) and confusing the final /zi/ with /si/ or /zi/ as /zɪ/ or /ziː/. Also, speakers may merge /proʊ/ and /pro/ into a flat vowel. Correction: keep the diphthong /oʊ/ clearly, maintain secondary syllable stress on the middle syllable, and end with a crisp /zi/ (voiced z plus i). Practice with slow repetition and accurate IPA cues: lə-ˈproʊ-zi.
In US English, you’ll hear /ləˈproʊzi/ with rhoticity—the first /r/ is pronounced after the vowel. UK and AU variants use /ləˈprəʊzi/, with a more centralized first vowel and non-rhotic tendencies in some speakers, though many AU speakers are rhotic. The /oʊ/ diphthong in US corresponds to /əʊ/ in UK/AU. Final /zi/ remains the same phoneme, though vowel length can subtly differ.
Two main challenges: the two-syllable rhythm with a strong middle syllable and the /oʊ/ diphthong followed by a voiced /z/ sound. It’s easy to misplace stress or shorten the middle vowel. Another pitfall is blending the final /zi/ with a following word. Focused practice on the /ˈproʊ/ vs /ˈprəʊ/ and keeping the final z sound crisp will help.
Yes—watch the transition between the stressed syllable and the final syllable: /ˈproʊzi/ requires a clean glide from /oʊ/ into /z/ without inserting extra schwa. The /l/ at the start should be light, and the /r/ in rhotic variants should be clearly pronounced or avoided depending on the accent. In careful enunciation, aim for a bright /oʊ/ or /əʊ/ before the final /zi/.
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US differences: rhotic /r/ is pronounced; middle vowel is /oʊ/ with a clear glide, final /zi/ voiced. UK/AU: often non-rhotic or light /r/; middle vowel may be /əʊ/ and the first vowel can be more centralized. Vowel quality: US typically taller mouth opening; UK/AU may be flatter and more relaxed jaw. IPA cues: US /ləˈproʊzi/; UK/AU /ləˈprəʊzi/. Consonants: /l/ is light, /r/ can be tapped or approximant in US; in UK/AU you may substitute a weaker /r/ or none in syllables without rhotic pronunciations. Practice with minimal pairs that stress the middle syllable.
Leprosy comes from the Greek lepros, meaning “scaly” or “scaly disease.” The term entered late Latin as lepra, then Old French lepra, and finally English as leprosy in the medieval period. The modern medical term Hansen’s disease honors Gerhard Armauer Hansen, who identified the causative bacillus Mycobacterium leprae in 1873 and clarified the infectious nature of the disease. Over centuries, medical understanding evolved from moral judgment and religious stigma to a focus on bacterial etiology, diagnosis, and antibiotic treatment. The shift away from punitive isolation toward public health management began in the 20th century, with multidrug therapy achieving high cure rates. First known use in English appears in late medieval medical texts, with the term coexisting alongside traditional diagnoses until pharmacological advances redefined treatment and social attitudes toward the disease.
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Words that rhyme with "Leprosy"
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