4 syllables: Ni, fe, di, pine. Stress on fe.
neye-FED-uh-peen
/ˌnaɪˈfɛdəpin/
Nifedipine is pronounced neye-FED-uh-peen (/ˌnaɪˈfɛdəpin/). It has four syllables (Ni-fe-di-pine), with the stress on "fe". Nifedipine is a prescription calcium channel blocker used to treat high blood pressure and angina. It is a chemical compound name formed from the dihydropyridine class and a nitrile-derived root, pronounced with a four-syllable pattern. In medical contexts, it’s common in pharmacology and patient education materials, and the pronunciation is important for clear clinician communication and medication naming.
nounNifedipine is a prescription calcium channel blocker used to treat high blood pressure and angina. It is a chemical compound name formed from the dihydropyridine class and a nitrile-derived root, pronounced with a four-syllable pattern. In medical contexts, it’s common in pharmacology and patient education materials, and the pronunciation is important for clear clinician communication and medication naming.
- You focus only on the first syllable and say NI-fe-di-pin with misaligned stress; ensure the stress falls on the third syllable (DI). - Do not reduce the middle syllable to a schwa; keep /ˈdiː/ or /diː/ for clarity. - Final consonant cluster is simple, avoid adding extra syllable; close with /pin/ or /pin/ with a crisp final n. - Slow, deliberate practice is best; do not rush to sound natural; accuracy first.
How to Pronounce Nifedipine
"The patient was prescribed nifedipine to manage essential hypertension."
"Nifedipine tablets are available in extended-release formulations."
"The pharmacist demonstrated the correct pronunciation of nifedipine before dispensing."
US/UK/AU pronunciation follows the same four-syllable pattern: ni-fe-DI-pin. IPA: US /ˌnɪfəˈdiːpin/; UK /ˌnɪfəˈdiːpin/; AU /ˌnɪfəˈdɪpiːn/. Emphasize the middle syllable DI with a long E in the final -pine sound. Tip: start with NI (short i), then FE (schwa-like or short e) depending on dialect, then DI (stress), then PIN (/piːn/). Practicing with a slow, deliberate articulation helps ensure the long vowel in the second-to-last syllable lands correctly.
Common errors: misplacing stress (placing it on NI or NE), slurring the final -pine into a nasal; pronouncing the second syllable as /fə/ rather than /fəˈdiː/. Correction: clearly mark the syllables ni- fe- DI- pin, with DI carrying primary stress and the final -pine producing a long /iːn/ or /pin/ final. Use slow pronunciation first: /ˌnɪfəˈdiːpin/ and then speed up. Focus on keeping the long middle vowel and crisp final consonant.
In US/UK/AU, the main difference is vowel quality: US often uses /ˈdiː/ for the penultimate vowel, UK/AU may be similar but with a slightly more clipped /iː/ in some speakers. Rhoticity is not a major issue here (nonnasal r-coloration). The final -pine is typically /pin/ or /piːn/ in most dialects. Overall, the primary stress remains on the third syllable (DI).
Some challenges: the four-syllable, multisyllabic medical term with a heavy DHP suffix -dipine; the long fronted vowel in the penultimate syllable; subtle differences between /iː/ and /ɪ/; and keeping the rhythm with four evenly stressed-ish segments. You’ll hear longer duration on the DI in rapid clinical speech. Practicing with IPA and slow articulation helps you retain the correct vowel quality and stress pattern.
It combines a non-native sounding cluster '-dipine' with a dihydropyridine core. The key phonetic landmarks are the clear four-syllable division ni-fe-di-pine, primary stress on DI, and a long vowel in the final -pine. Native speakers keep the stress stable even in fast medical conversations, so practicing with short chunks helps you maintain accuracy.
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- US: rhotics, slight lengthening of the second syllable; keep /ˈdiː/ in US. - UK: crisp /ˈdiː/; less vowel length variation; non-rhotic? You still pronounce r in final; - AU: similar to UK; sometimes more clipped. - IPA references: US /ˌnɪfəˈdiːpin/; UK /ˌnɪfəˈdiːpin/; AU /ˌnɪfəˈdɪpiːn/ (note the final vowel shift).
Nifedipine derives from the chemical naming conventions of the dihydropyridine (DHP) class of calcium channel blockers. The root nifedipine likely reflects a truncated form of related dihydropyridine core names and substituents used in medicinal chemistry in the mid-20th century. The term is built from parts that indicate its dihydropyridine ring (a six-membered ring with two adjacent double bonds), the ‘-dipine’ suffix historically linked to this chemical class (analogous to other DHPs like felodipine, nifedipine, nimodipine). The prefix “nife-” or “ni-
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💡 These words have similar meanings to "Nifedipine" and can often be used interchangeably.
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Words that rhyme with "Nifedipine"
-ned sounds
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