5 syllables: Ma, le, i, mi, de. Stress on Ma.
MAY-lim-eyed
/ˈmeɪlɪmaɪd/
Maleimide is pronounced MAY-lim-eyed (/ˈmeɪlɪmaɪd/). It has five syllables (Ma-le-i-mi-de), with the stress on "Ma". Maleimide is a bicyclic organic compound featuring a five-membered imide ring fused to a second ring, typically used as a reactive dienophile in cycloadditions. It exists as derivatives with varying N-substituents and is valued for its electron-poor double bond. In chemistry contexts, it’s recognized for its reactivity in polymerization and click chemistry applications.
nounMaleimide is a bicyclic organic compound featuring a five-membered imide ring fused to a second ring, typically used as a reactive dienophile in cycloadditions. It exists as derivatives with varying N-substituents and is valued for its electron-poor double bond. In chemistry contexts, it’s recognized for its reactivity in polymerization and click chemistry applications.
How to Pronounce Maleimide
"The researcher used maleimide as a dienophile in a Diels–Alder reaction."
"Pure maleimide can polymerize under high temperatures without a catalyst."
"The synthesis protocol requires N-substituted maleimide derivatives for selective reactivity."
Pronounce it as mah-lee-MY-id with primary stress on the second syllable. The IPA is /ˌmæ.liˈmaɪd/ in US and UK usage, with the Australian variant matching /ˌmæ.liˈmaɪd/. Break it into syllables: /ˌmæ/ (mah) /li/ (lee) /ˈmaɪd/ (myd). Tip: keep the final /d/ crisp and avoid turning it into a /t/.
Common errors include stressing the wrong syllable (emphasizing the first or third instead of the second), pronouncing /æ/ as a short a in all syllables, and softening the final /d/ into a /t/ or (/də/). Correction: place primary emphasis on /ˈmaɪd/; keep /æ/ as a clear, short vowel in the first syllable while maintaining a short, crisp /d/ at the end. Practice by saying /ˌmæ.liˈmaɪd/ slowly, then at natural speed.
In US and UK, the second syllable carries primary stress: /ˌmæ.liˈmaɪd/. US tends to be rhotic with a pronounced /r/ only when present in adjacent words; the vowel in the first syllable remains /æ/; UK often displays slightly crisper consonants and similar stress. Australian pronunciation mirrors UK/US patterns but may be run together more in rapid speech. The final /d/ remains a dental/alveolar stop in all typical varieties.
The difficulty lies in the three-syllable structure with a shifted primary stress on the final syllable and the diphthong in /maɪd/. The combination of /æ/ and the final /d/ requires careful articulation to avoid chewing into a /t/ or elongating the vowel. Also, the -li- syllable needs a clean light /l/ followed by a quick /i/: /liː/ vs /li/. Focus on segment boundaries and steady rhythm.
A distinctive feature is the compact final /maɪd/ part which can trigger a slight vowel reduction in very fast speech, but in formal contexts you should maintain the full /maɪd/. The preceding /mæ/ should be clearly voiced and not reduced. Ensure the liaison between /li/ and /maɪd/ remains crisp to preserve distinct syllables in rapid lab speech.
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US: rhoticity and a clearer /æ/; UK: crisper consonants, non-rhotic but clear /r/ absent; AU: similar to UK/US but more relaxed rhythm; all share primary stress on the final syllable /maɪd/. Vowels: US /æ/ vs UK /æ/ as well; /i/ in /li/ tends to be shorter in casual speech; /maɪd/ maintains a tight diphthong. IPA references: /ˌmæ.liˈmaɪd/. Practice: exaggerate the second syllable briefly to locate the peak of the stress, then normalize.” ,
The term maleimide derives from the maleic anhydride and imide functional group origins. It begins with the maleic component from maleic acid (hydrogen maleate) and the imide suffix denoting a nitrogen-containing cyclic imide structure. The basic skeleton was elaborated in the 19th to 20th centuries as chemists explored anhydride-derived ring systems and their condensation products. The “malei-” portion references maleic, a common diprotic acid precursor, while the “-mide”/“-imide” suffix reflects the imide linkage formed through condensation with amines or ammonia. Early work on cyclic imides in the late 1800s and early 1900s established the behavior of maleimide-like rings as electron-deficient dienophiles. The modern, widely used maleimide monomers for polymer chemistry emerged with advances in Diels–Alder chemistry and vinyl imide chemistry in the mid-20th century, enabling efficient cycloadditions and cross-linking. First reputable syntheses and characterizations appeared in the literature as researchers sought stable, reactive, N-substituted derivatives for targeted applications in materials science and bioconjugation. Over time, “maleimide” has become a standard term in organic synthesis, particularly regarding thiol-addition and click-chemistry contexts, with commercial availability expanding to various N-substituted variants for tailored reactivity and solubility.
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Words that rhyme with "Maleimide"
-ile sounds
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