3 syllables: i, so, tope. Stress on i.
EYE-suh-tohp
/ˈaɪsəˌtoʊp/
isotope is pronounced EYE-suh-tohp (/ˈaɪsəˌtoʊp/). It has three syllables (i-so-tope), with the stress on "i". Isotope is a variant of an element whose atoms share the same number of protons but have different numbers of neutrons, resulting in different atomic masses. The term is used in science contexts to discuss nuclear properties, stability, and isotopic abundance. In everyday language, it often appears in chemistry or physics discussions, especially regarding radioisotopes and stable isotopes. The word itself is borrowed from Greek roots and is commonly pronounced with three syllables: i-so-tope.
Isotope is a variant of an element whose atoms share the same number of protons but have different numbers of neutrons, resulting in different atomic masses. The term is used in science contexts to discuss nuclear properties, stability, and isotopic abundance. In everyday language, it often appears in chemistry or physics discussions, especially regarding radioisotopes and stable isotopes. The word itself is borrowed from Greek roots and is commonly pronounced with three syllables: i-so-tope.
"The researchers labeled the sample with a stable isotope to track metabolic pathways."
"Different isotopes of carbon, such as carbon-12 and carbon-14, have different masses."
"Radioisotopes are used in medical diagnostics and treatment."
You say it as IS-uh-tope, with primary stress on the first syllable. IPA US: /ˈaɪ.səˌtoʊp/, UK/AU: /ˈaɪ.səˌtəʊp/. The middle syllable is quick and light; the final -tope rhymes with 'hope'. Be sure to produce a clear /oʊ/ or /əʊ/ in the final syllable, not a schwa-dominant ending. Try saying it slowly: /ˈaɪ.sə.təʊp/ before speeding up to natural speech.—IPA and phonetic landmarks included.
Common errors: turning the middle 's' into a strong /z/ sound instead of a light /s/; misplacing the stress by saying ‘i-SO-tape’; mispronouncing the final diphthong as a short /ɪ/ or /ɒ/ instead of /oʊ/ or /əʊ/. Correction: keep /s/ as a voiceless sibilant between the first and second syllables, place the stress on IS, and finish with a clear /toʊp/ or /təʊp/. Practice with slow pace and mouth positions to lock the rhythm.
US: /ˈaɪ.səˌtoʊp/ with rhoticity; UK/AU: /ˈaɪ.səˌtəʊp/, non-rhotic or reduced rhoticity in some contexts. The final vowel is a true diphthong in both UK and US, but Americans may glide more toward /oʊ/ than the British /əʊ/. Mouth posture: starter position with rounded lips for /oʊ/ and a light, quick /s/ between first two syllables. Accent differences are subtle but noticeable in the final diphthong and the rhythm of the second syllable.
Two main challenges: the three-syllable rhythm with quick middle / sə/ timing, and the final /toʊp/ vs /təʊp/ diphthong realization. Some learners also mishear or misproduce /aɪ/ as /iː/ or /ɪ/, and may overpronounce the second syllable. Focus on keeping the first syllable stressed, a crisp /s/ in the middle, and ending with a clear, rounded /oʊ/ or /əʊ/ to avoid truncation. IPA cues support precise articulation.
There are no silent letters in isotope; the stress pattern is strong on the first syllable (IS-o-tope) with secondary emphasis possible on the final syllable in careful speech. Pay attention to the middle /s/ as a soft, voiceless sound, and ensure the final /tope/ or /teʊp/ carries a full diphthong to avoid a clipped ending. This yields a natural, scientifically precise pronunciation.
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Isotope comes from the Greek roots 'isos' meaning 'equal' and 'topos' meaning 'place' or 'position'. The term was coined in the early 20th century to describe atoms of the same element that occupy the same position in the periodic table (same number of protons) but differ in mass due to varying neutron counts. The concept emerged from the work of Frederick Soddy and others who recognized that chemical properties are governed by protons, while physical properties like atomic mass vary with neutrons. The first formal recognition of isotopes occurred around 1913–1914 in the context of early mass spectrometry and radiochemistry, including discoveries related to uranium and other elements. Over time, isotopes became central to fields ranging from radiometric dating to medical imaging. The language of origin is Greek, with 'isos' (equal) and 'topos' (place), literally describing atoms occupying the same place in the periodic table yet differing in mass. The term has since become foundational in chemistry, physics, geology, and environmental science, reflecting the nuance that identical chemical behavior can cloak different nuclear identities. Modern usage spans stable and radioactive isotopes, with precise notation like 14C or 235U indicating specific neutron counts. The historical development traces the shift from purely chemical understanding to recognizing nuclear properties, propelling advances in dating techniques, tracing metabolic pathways, and improving diagnostic tools.
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💡 These words have similar meanings to "isotope" and can often be used interchangeably.
🔄 These words have opposite meanings to "isotope" and show contrast in usage.
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Words that rhyme with "isotope"
-ope sounds
Practice with these rhyming pairs to improve your pronunciation consistency:
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