4 syllables: gra, nu, lo, ma. Stress on lo.
gran-yuh-LOH-muh
/grænjəˈloʊmə/
granuloma is pronounced gran-yuh-LOH-muh (/grænjəˈloʊmə/). It has four syllables (gra-nu-lo-ma), with the stress on "lo". Granuloma is a small area of inflammation, typically a cluster of immune cells, which forms in response to infection, injury, or irritants. It can occur in various tissues, often indicating a chronic or persistent immune reaction. The term is used across medical and scientific contexts to describe this nodular inflammatory process.
Granuloma is a small area of inflammation, typically a cluster of immune cells, which forms in response to infection, injury, or irritants. It can occur in various tissues, often indicating a chronic or persistent immune reaction. The term is used across medical and scientific contexts to describe this nodular inflammatory process.
"- The biopsy revealed a granuloma in the lymph node."
"- Doctors considered granuloma formation as part of the chronic inflammatory response."
"- A granuloma can complicate healing after tuberculosis exposure."
Granuloma is pronounced gra-NOO-loh-muh in many English contexts, with primary stress on the second syllable: /ɡræn.juˈloʊ.mə/ in US English or /ɡræn.jəˈluː.mə/ in many UK variants; some Australian speakers lean toward /ɡræn.jəˈluː.mə/. Break it into four syllables: gran-u-lo-ma, with emphasis on LO. The initial 'gran' rhymes with 'gran-' in grand, the second syllable uses a schwa or a reduced vowel depending on accent, and the final '-ma' is a light, unstressed syllable.
Common errors: misplacing stress, saying 'GRAM-u-LOH-ma' instead of stressing the second syllable; pronouncing the second syllable as a full 'oo' as in 'groom' rather than a short 'u' or schwa; and melding the final '-ma' too strongly, yielding 'gran-u-LOH-mah' with excessive vowel length. Correction: keep four distinct syllables with primary stress on the second-to-last? Actually on the third syllable: gra-NU-lo-ma? Wait: In granuloma, the stress is on the third syllable in many variants: gra-NYU-lo-ma? The correct pattern is gra-NOO-loh-muh for US; the second syllable houses a long 'oo' sound /uː/ or a close back rounded vowel; ensure final 'ma' is light. Practice by isolating /ˈɡræn.juˈloʊ.mə/ (US) or /ˈɡræn.jəˈluː.mə/ (UK/others).
US English typically: /ɡræn.juˈloʊ.mə/, with clear /ju/ in the second syllable and final schwa. UK/other non-rhotic variants may show /ˈɡræn.jəˈluː.mə/ or same pattern with a reduced second vowel and a slightly longer final /ə/; Australian tends toward /ˈɡræn.jəˈluː.mə/ with non-rhotic tendencies and a reduced second vowel, but some speakers retain /ju/ in the second syllable. Across accents, the main variation is the nucleus of the second syllable: /juː/ vs /jə/ and rhoticity affecting the r-like quality in connected speech.
Difficulties arise from four-syllable timing, the blend of /j/ after the /n/ in the second syllable, and the final unstressed schwa. The sequence /ˈɡræn.juˌloʊ.mə/ involves a palatal approximant in the second syllable and a rising-tending diphthong in /oʊ/. Some speakers insert an extra syllable or distort the second vowel to /ə/ or /u/. Also, medical terms often combine Latin roots with Greek suffix '-oma,' which can lead to variable stress placement in rapid speech.
The term combines a Latin root with Greek suffix and has a distinctive four-syllable cadence. Unique questions include whether to articulate the second syllable as /ju/ or /jə/ and where to place primary stress in rapid clinical narration. For clarity, you’ll want to keep /ˈɡræn.juˈloʊ.mə/ in US speech, but be aware of /ˈɡræn.jəˈluː.mə/ in some UK/Australian variants. Focus on the four distinct syllables and the non-syllabic vowel in the middle.
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Granuloma comes from late Latin granuloma, formed from granul- ‘granule’ (Latin granulum) + -oma (a suffix denoting a swelling or tumor, from Greek -ōma). The root gran- signals small grain-like particles or cells. The medical term evolved in the 19th and early 20th centuries as histology and pathology developed, to describe nodular inflammatory lesions composed of macrophages, giant cells, and other immune cells arranged in granulomatous structures. The concept of granulomas arose from microscopical observations of chronic inflammatory responses, first recognized in relation to diseases like tuberculosis and sarcoidosis, where organized cellular aggregates form in tissue as a defense mechanism. The word’s usage broadened to describe any localized nodular inflammation across body tissues, while its precise cellular composition and causative agents vary by condition. The term remains central in medical diagnostics, radiology, and pathology to indicate a granulomatous response rather than a simple inflammatory edema.
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Words that rhyme with "granuloma"
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