4 syllables: gem, fib, ro, zil. Stress on gem.
GEM-fib-roh-zuhl
/ˈɡɛmfɪbɹoʊzəl/
gemfibrozil is pronounced GEM-fib-roh-zuhl (/ˈɡɛmfɪbɹoʊzəl/). It has four syllables (gem-fib-ro-zil), with the stress on "gem". Gemfibrozil is a lipid-lowering prescription medication in the fibrate class. It influences triglyceride and HDL cholesterol levels by activating PPAR-α receptors, reducing hepatic VLDL production and enhancing lipolysis of triglyceride-rich particles. It’s typically prescribed for dyslipidemia and specific hypertriglyceridemia cases, administered orally in tablet form under medical supervision.
Gemfibrozil is a lipid-lowering prescription medication in the fibrate class. It influences triglyceride and HDL cholesterol levels by activating PPAR-α receptors, reducing hepatic VLDL production and enhancing lipolysis of triglyceride-rich particles. It’s typically prescribed for dyslipidemia and specific hypertriglyceridemia cases, administered orally in tablet form under medical supervision.
"The patient was prescribed gemfibrozil to help reduce very high triglycerides."
"Gemfibrozil is often used when statins alone don’t adequately control lipid levels."
"She reported no adverse interactions after starting gemfibrozil with her dietary changes."
Pronounce as juhm-FEE-broh-zil with primary stress on the second syllable. IPA US: dʒɛmˈfɪbroʊzɪl; UK: dʒɛmˈfɪbrəʊzɪl; AU: dʒɛmˈfɪbrəzɪl. Start with a soft 'j' /dʒ/, then 'em' as in 'them,' stress on the 'fi' part, and end with a clear 'zil'.
Common errors: stressing the wrong syllable (e.g., /ˈdʒɛmfɪbroʊ/), mispronouncing the middle consonants as /brə/ instead of /broʊ/ or /brə/; and truncating the final -zil to -zɪl in quick speech. Correction tips: emphasize the second syllable with a tight jaw and a long /i/ vowel in /fɪ/; maintain the /broʊ/ or /broʊzɪl/ vowel quality for the final two syllables; practice slow shadowing to fix the stress pattern: jewm-FEE-bro-zil.
In US English, the final syllable tends toward /zɪl/ with a slightly stronger vowel; UK and AU often realize the middle vowel as /brəʊ/ or /brəʊzɪl/ with a more rounded onset in the /broʊ/ region. The main difference is rhotics and vowel quality: US rhotics influence the /ɹ/; UK and AU may have a more non-rhotic quality in rapid speech, affecting the /bros/ cluster. Overall, keep the second syllable as /ˈfɪbroʊ/ (US) vs /ˈfɪbrəʊ/ (UK/AU) and end with /zɪl/ or /zəl/ depending on pace.
Difficulties come from the consonant cluster -mf- after the initial 'gem' and the long vowel in the middle syllable, plus the final '-zil' cluster that can sound like /zɪl/ or /zəl depending on tempo. The multisyllabic, medical word also has less-common phonemes for some speakers, including the initial /dʒ/ and the mid diphthong in /broʊ/ or /brəʊ/. Focus on keeping syllable boundaries clear and the primary stress on the second syllable.
A distinctive feature is the heavy emphasis on the syllable /fɪb/ (the second syllable), which anchors the word’s rhythm. The /g/ at the start is a soft, /dʒ/ sound, not a hard /g/. The final /zɪl/ or /zəl/ should remain crisp, with a light but audible z-voicing. Remember the middle -bro- portion carries both a rounded vowel and a glide that shapes the word’s overall cadence.
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US: rhotic /ɹ/ and clearer /oʊ/ in /broʊzɪl/. UK/AU: non-rhotic tendencies can soften the /ɹ/; vowel in /broʊ/ may be realized as /brəʊ/. Use IPA benchmarks: US US: /dʒɛmˈfɪbroʊzɪl/; UK/AU: /dʒɛmˈfɪbrəʊzɪl/. Practice with mouth in higher F1/F2 positions for the vowel quality, and keep final z-voicing.
Gemfibrozil derives from the chemical naming convention of fibric acid derivatives used historically in lipid management. The root fibr- signals the fibric acid family, while the -fibrozil suffix marks a substituted aryl-fibric compound. The term likely emerged in the mid-20th century as medicinal chemistry advanced beyond simple antilipemic agents to targeted PPAR-α agonists. Its first recorded usage appears in pharmacology literature around the 1960s–1970s as researchers classified newer fibrates for triglyceride lowering. Over time, gemfibrozil established itself as a distinct molecule within this class, with brand names and generics reflecting its chemical identity. The word is primarily used in English-language medical texts and prescribing information, with its pronunciation preserved across dialects due to standardized pharmaceutical nomenclature.
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Words that rhyme with "gemfibrozil"
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