5 syllables: chro, ma, to, graph, y. Stress on to.
kroh-muh-TAH-gruh-fee
/kɹoʊməˈtɑɡɹəfi/
chromatography is pronounced kroh-muh-TAH-gruh-fee (/kɹoʊməˈtɑɡɹəfi/). It has five syllables (chro-ma-to-graph-y), with the stress on "to". Chromatography is a laboratory technique for separating mixtures into individual components based on differential movement through a medium under the influence of a solvent. It relies on varying interactions between the components and the stationary phase, allowing identification and quantification of substances. The term encompasses several methods (e.g., gas, liquid, and paper chromatography) used across chemistry, biology, and environmental science.
Chromatography is a laboratory technique for separating mixtures into individual components based on differential movement through a medium under the influence of a solvent. It relies on varying interactions between the components and the stationary phase, allowing identification and quantification of substances. The term encompasses several methods (e.g., gas, liquid, and paper chromatography) used across chemistry, biology, and environmental science.
"The scientist demonstrated chromatography to separate the dye components."
"Gas chromatography was employed to analyze volatile compounds in the sample."
"Paper chromatography provided a quick qualitative profile of the pigments."
/ˌkrɒ.məˈtɒɡ.rə.fi/ in US and UK styles broadly follow the pattern kri-MA-toh-gruh-fee. Stress lands on the third syllable: chro-MA-tog-raphy in many pronunciations, but for clarity: /ˌkrɒməˈtɒɡrəfi/ can be heard as CHRO-ma-TOG-ra-phy. Start with a light 'kro' then move to a stressed 'to' or 'tog' segment, finishing with 'phy' as /fi/. Mouth positions: back of the tongue raises for /ɒ/ vs /ɑ/ in American pronunciations; keep the /ɡ/ plosive clean, and end with a crisp /fi/.
Two frequent errors: (1) misplacing stress, saying chro-MA-tog-raphy or chro-ma-TOG-ra-phy; keep the stress on the third syllable. (2) mispronouncing the middle /tɒɡ/ as /təɡ/ or slurring /ɡrə/ into /ɡrə/; articulate the /t/ clearly before /ɒɡ/ and separate the /rə/ in the second half. Practice with the across-the-lane rhythm: /ˌkrɒməˈtɒɡrəfi/ and emphasize the 'tɒɡ' cluster before the final /rəfi/.
In US English, rhoticity means /ˌkrɒməˈtɒɡrəfi/ with an r-like quality following vowels, and the /ɒ/ as in 'hot'. UK English often yields /ˌkrəʊˈmæɒɡrəfi/ with non-rhoticity: most Americans hear /ˌkrɒməˈtɒɡrəfi/ while Britons may produce a broader /əʊ/ and a slightly longer second vowel. Australian tends to be rhotic but with a more centralized vowel in the second syllable, and /ɡrəfi/ endings can be slightly softer. Core structure remains but vowel quality and rhotics vary: stress position is stable on MA- or TOG- depending on speaker.
The difficulty comes from the long, multi-syllabic sequence with adjacent consonant cluster /tɡ/ and a secondary stress near the middle. The sequence -mo-tog- has a tight consonant transition, and the final -phy is pronounced /fi/ rather than /fiː/ in many dialects. Also, the initial 'chro' can signal /kro/ rather than /t͡ʃro/ for some speakers, and the rapid pace makes the /ɡrəfi/ ending blur. Focus on splitting into syllables and articulating each consonant clearly.
The unique feature is the three-stage syllable pattern with the central 'ma' and 'tog' boundary, where the /ə/ or /ɒ/ vowels alternate in American vs. British English. The secondary stress is on the -to- or -tog- segment depending on speaker, but in formal lab contexts you’ll often hear very clear enunciation of the /tɒɡ/ cluster and demand precise lip/jaw positioning to avoid slurring the /ɡrəfi/ ending.
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Chromatography derives from the Greek words chroma (color) and graphia (writing). The term was coined in the early 20th century to describe the separation of colored compounds as a function of their differential movement on a stationary phase. The concept grew from observations of dye separations in paper and thin-layer chromatography and was formalized as techniques like column, gas, and later high-performance liquid chromatography expanded. First used in scientific literature around 1900–1910 in references to color-based separations, the method matured through the 20th century with advances in instrumentation, detectors, and theoretical understanding of partitioning, adsorption, and diffusion. Today, chromatography denotes a family of techniques for separating substances based on interactions with a stationary phase and a mobile phase, applied broadly from analytical chemistry to biochemistry and environmental testing.
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💡 These words have similar meanings to "chromatography" and can often be used interchangeably.
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Words that rhyme with "chromatography"
-phy sounds
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