4 syllables: a, pix, a, ban. Stress on pix.
uh-PIK-suh-ban
/əˈpɪksəbæn/
apixaban is pronounced uh-PIK-suh-ban (/əˈpɪksəbæn/). It has four syllables (a-pix-a-ban), with the stress on "pix". Apixaban is a direct oral anticoagulant used to reduce stroke risk in atrial fibrillation and to treat and prevent blood clots. It belongs to the class of factor Xa inhibitors and is taken as pills. The name is of Latinized origin and is pronounced with multiple syllables, with stress on the third syllable in typical usage.
Apixaban is a direct oral anticoagulant used to reduce stroke risk in atrial fibrillation and to treat and prevent blood clots. It belongs to the class of factor Xa inhibitors and is taken as pills. The name is of Latinized origin and is pronounced with multiple syllables, with stress on the third syllable in typical usage.
- You might drop the x to an /ks/ cluster instead of the accurate /gz/ after /ɡ/; fix by slowing and enunciating the /ɡz/ sequence, then blend smoothly into /æ/. - Stress misplacement is common: place the primary stress on the third syllable; practice clapping the rhythm: a-pi-GZ-a-ben. - The final 'ban' may reduce to 'bun' or 'ben'; keep the final /ən/ with a light /b/ onset before it. - Record yourself and compare to reference pronunciations to ensure you’re not muting the zh-like sound in /gz/.
"You should take apixaban twice daily with a full glass of water."
"The clinical trial evaluated apixaban as an alternative to warfarin."
"Patients must monitor for signs of bleeding while on apixaban."
Pronounce as /ˌæ-pɪ-ˈɡzæ-bən/ (US/UK/AU share) with primary stress on the third syllable. Break it into four sounds: a-pix-a-ban. Start with a clear 'a' as in 'cat', then 'p' followed by a light 'i' vowel, then the 'gzab' cluster where the 'gz' is a voiced 'z' after a hard 'g' onset, and finish with a soft 'an' (schwa + n). Keep the 'x' as a single /gz/ blend, not /ks/ or /z/. Audio resources: consult Cambridge or Oxford dictionaries or Forvo to hear native pronunciations.
Common errors: 1) stressing the wrong syllable (putting emphasis on 'a' or 'xa' instead of 'ban'); 2) pronouncing the 'x' as /ks/ or /z/ instead of the /gz/ blend after /ɡ/; 3) mispronouncing the final 'ban' as 'van' or 'bahn' with non-stressed vowels. Correction tips: practice the four-syllable rhythm with a clear /ɡz/ sequence after the /p/ and /i/; keep the 'a' in the third syllable shortened and stressed: /ˌæ-pɪ-ˈɡzæ-bən/. Listen to native examples and mimic the stress pattern.
In US, UK, and AU, the vowel qualities are similar, but rhoticity can influence the 'r' sounds in connected speech; however, 'apixaban' contains no /r/. The main variation is subtle vowel length and intonation: US may have a slightly sharper /æ/ in the first syllable and a more pronounced /ɪ/ after the /p/. The /ˈɡz/ cluster tends to be realized with a crisp, voiced affricate after /pɪ/. Overall, all three share /ˌæ-pɪ-ˈgˈzæ-bən/ with minor reductions in rapid speech.
The primary challenges are the consonant cluster /gz/ following /pɪ/ and the unstressed final syllable /-bən/, which can sound like /-bn/ or /-ən/ in fast speech. Additionally, the sequence 'pix' may tempt a simpler /pɪks/ pronunciation; keep the /gz/ blend and the dental-alveolar alternation of the 'z' sound. Practice with slow articulation: /ˌæ-pɪ-ˈgzæ-bən/ and then speed up, ensuring the /z/ remains voiced and the /g/ is attached to the prior vowel.
No part of 'apixaban' is truly silent in careful speech. In quick, clinical speech, the final /n/ might be lightly reduced or devoiced, but authentic pronunciation preserves /bən/ at the end. The critical features—/æ/ in the first syllable, the /p/ closure, the /ɡz/ blend, and the unstressed ending /-bən/—should remain audible for clear communication.
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- US: non-rhotic tendencies are not a factor here; still, the /ɡ/ onset of the /gz/ cluster should be clean and the /æ/ of the first syllable should be slightly lax. - UK: maintain the same four syllables, with possibly more vowel shortening in the second syllable; emphasize the /gz/ cluster clearly. - AU: similar to US/UK but with more prominent vowel rounding in the final /ən/; ensure the /z/ is voiced and the /g/ is attached to the /i/ vowel.
Apixaban derives from the pharmaceutical naming conventions used for synthetic small-molecule drugs. The prefix 'api-' is not a standalone root with a fixed meaning and is likely a phonotactic construction chosen to produce a distinctive, pronounceable brand-like name. The suffix '-aban' echoes other anticoagulants in common usage (e.g., 'apixaban' mirrors '-iban' and '-aban' patterns found in drug names to convey a robust, professional sound). The term lacks a direct Latin or Greek morpheme with a semantic meaning; instead, it is an artificially coined, non-derived label created by a pharmaceutical company for regulatory uniqueness. First uses of apixaban appeared in late 2000s within clinical research and later in commercial products, with rapid uptake after pivotal trials demonstrated efficacy and safety in reducing stroke risk in atrial fibrillation. As a brand-name-like chemical label, its history is tied to drug development, regulatory approvals, and post-approval pharmacovigilance rather than centuries of linguistic evolution.
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Words that rhyme with "apixaban"
-can sounds
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