Wernicke-Korsakoff Syndrome is a neurological disorder caused by severe thiamine (vitamin B1) deficiency, typically linked to chronic alcohol misuse or malnutrition. It comprises two linked conditions: Wernicke’s encephalopathy (acute) and Korsakoff’s psychosis (chronic). It presents with ataxia, confusion, nystagmus, and amnesia, and requires urgent treatment to prevent persistent deficits.
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