Thiazolidinedione is a class of heterocyclic organic compounds used primarily as insulin-sensitizing drugs in the treatment of type 2 diabetes. The term designates the thiazolidine ring fused to a dione (two ketone groups), reflecting its core structure. In pharmacology, it refers to compounds like pioglitazone and rosiglitazone that modulate PPAR-γ receptors to improve insulin sensitivity.
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