Sistine Chapel is the famed Vatican chapel adorned with Michelangelo’s frescoes. As a proper noun, it refers to the specific architectural space and its art, not a general chapel. The pronunciation emphasizes two stressed syllables, with a clear initial /ˈsɪs.tiːn/ for Sistine and /ˈtʃæp.əl/ for Chapel, totaling a two-word name often treated as a compound proper noun in English speech.
Full pronunciation guide
