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How to pronounce Oligonucleotide

How to Pronounce "Oligonucleotide"

Definition: How to say "Oligonucleotide" and use it in a sentence

Phonetic Spelling:

ah-lee-go-NOO-klee-uh-tide (oligonucleotide)

How to say "Oligonucleotide" correctly

Here are some definitions of Oligonucleotide.

  • A short nucleic acid strand, typically consisting of up to 20 nucleotides, used in molecular biology and genetic testing.
  • A molecule made up of a small number of nucleotides linked together.
  • A short DNA or RNA molecule, typically with a sequence of 20 nucleotides or fewer, used in genetic research and biotechnology.
  • A short segment of DNA or RNA, usually consisting of 20 or fewer nucleotides, that serves as a primer or probe in genetic testing or research.
  • A small piece of nucleic acid, usually made up of 20 or fewer nucleotides, used in various biological applications.

Use Oligonucleotide correctly with these examples:

  • The scientist used an oligonucleotide as a primer in the polymerase chain reaction (PCR).
  • Oligonucleotides are essential tools in genetic engineering and biotechnology.
  • The lab is synthesizing custom oligonucleotides for their research project.
  • Sequencing technologies rely on the use of oligonucleotides to identify specific DNA sequences.
  • The pharmaceutical company is developing oligonucleotide-based therapies for genetic disorders.

Words close in sound to Oligonucleotide:

Oligopoly, Oligosaccharide, Oligarchy, Oliguria, Oligodendrocyte, Oligocene, Oligomer, Oligophagous, Oligotrophic, Oligohydramnios,

Synonyms for Oligonucleotide

Oligo, Short nucleic acid strand, Nucleotide sequence, DNA fragment, RNA oligomer, Gene probe, Molecular primer, Genetic oligo, Nucleic acid oligomer, Biotech oligonucleotide,

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Ways you can improve your pronunciation of ‘Oligonucleotide’

Some tips that should help you perfect your pronunciation of ‘Oligonucleotide‘:

  • Try to Break ‘Oligonucleotide’ down into each individual vowel, speak it aloud whilst exaggerating each sound until you can consistently say it without mistakes.
  • Record yourself saying ‘Oligonucleotide‘ in full sentences and then watch or listen back. You should be able to find any of your flaws quite easily.
  • Find pronunciation tutorials on Youtube or Google on how to pronounce ‘Oligonucleotide‘ correctly.
  • Target a single accent: mixing multiple accents can get really confusing, and not just beginners. So pick just one accent, perhaps US and stick to it!


A few more ideas to improve your English pronunciation skills, we recommend embrace these techniques:

Practicing speech contraction in speech is normal in the U.S. and is seen as a natural part of informal dialogue. For instance, changing “what are you going to do this weekend” to “what you gonna do this weekend” is commonplace. Look into terms like ‘gonna’ and ‘wanna’ for more insights.

Enhancing your intonation is crucial for English fluency. The ways you use stress, rhythm, and pitch in English are key in communicating your intended message and emotions. Numerous resources and videos on Youtube can aid you in learning these components to pronounce ‘Oligonucleotide’.

Engage with multiple Youtube channels dedicated to English learning. These platforms offer free resources that tackle important language skills. Pronounce.tv is another excellent source for honing your pronunciation.

Copying native speakers can greatly improve your pronunciation. Listen to how they pronounce ‘Oligonucleotide’ and attempt to replicate the tone, speed, and rhythm in your speech, making it second nature.

Incorporate phonetic exercises into your routine. Learning and practicing the phonetic sounds of English can help you accurately articulate ‘Oligonucleotide’.

Regularly use English in your daily conversations. The more you speak, the more adept you’ll become with the nuances of pronunciation and accent, improving your overall ability to communicate.

Frequently Asked Questions

I am unsure how to pronounce ‘oligonucleotide’, can you help?

Certainly! The correct pronunciation of “oligonucleotide” is oh-lee-go-NOO-klee-uh-tide. The word is broken down into syllables as “ol-igo-nu-cle-o-tide”. It is a term commonly used in biology and biochemistry to refer to a short chain of nucleotides (the building blocks of nucleic acids like DNA and RNA).

What do you mean by oligonucleotide?

Oligonucleotides are short sequences of nucleic acids, typically made up of 13 to 25 nucleotides. These molecules play a crucial role in various scientific fields such as research, genetic testing, and forensics. Oligonucleotides are designed to specifically bind to complementary DNA or RNA sequences through base pairing. They are used in techniques like polymerase chain reaction (PCR), DNA sequencing, and gene editing. Oligonucleotides are valuable tools in molecular biology and genetics due to their ability to target and interact with specific genetic sequences, allowing researchers to manipulate and study DNA and RNA with precision.

In what manner should one articulate ‘oligonucleotide’?

The word “oligonucleotide” should be articulated as “ol-uh-go-NOO-klee-uh-tide.” It is important to enunciate each syllable clearly and emphasize the correct stress on the syllables “NOO” and “klee” to ensure the word is pronounced accurately. Breaking down the word into its individual syllables can help in pronouncing it correctly: “ol” (as in the word “old”), “uh” (as in the word “up”), “go” (as in the word “go”), “NOO” (rhymes with “blue”), “klee” (rhymes with “flee”), and “uh-tide” (as in the word “tide”). Practice saying the word slowly and gradually increase the speed to feel more comfortable pronouncing it accurately.

Could you clarify the pronunciation of ‘oligonucleotide’?

The word “oligonucleotide” is pronounced as “ol-ih-go-NOO-klee-uh-tide.” Each syllable is stressed equally, with the emphasis on the third syllable “NOO.” The term is commonly used in genetics and molecular biology to refer to short sequences of nucleotides, typically less than 50 bases in length. It plays a crucial role in various biological processes, such as DNA replication, gene expression, and molecular diagnostics. Understanding the correct pronunciation of scientific terms like “oligonucleotide” is important for effective communication in academic and professional settings.

Would you kindly explain how to pronounce ‘oligonucleotide’?

The word ‘oligonucleotide’ is pronounced as “ol-ih-go-NOO-klee-oh-tide”. It is a term used in biochemistry to refer to short nucleic acid sequences, typically made up of 10 to 100 nucleotides. The pronunciation of ‘oligonucleotide’ may seem complex at first, but breaking it down into syllables can help in pronouncing it correctly. Just remember to emphasize the second syllable ‘go’ and the fourth syllable ‘klee’ to accurately pronounce ‘oligonucleotide’.

What is the structure of an oligonucleotide?

An oligonucleotide is a short chain of nucleotides, typically made up of about 10 to 20 nucleotides. The structure of an oligonucleotide is composed of a linear sequence of nucleotides linked together by phosphodiester bonds. Each nucleotide consists of a sugar molecule (either ribose or deoxyribose), a phosphate group, and a nitrogenous base (adenine, thymine, cytosine, or guanine). The nitrogenous bases of the nucleotides in an oligonucleotide determine its sequence and ultimately its function. In the snippet provided, the specific association with nickel ions and the involvement of the N7 atom of guanine suggest a specific interaction between the oligonucleotide and metal ions, which may have implications for its structure and function.

How does an oligos work?

Oligos, short for oligonucleotides, are synthesized through a chemical process called phosphoramidite chemistry. This process involves adding the four nucleic acids – adenine (A), thymine (T), cytosine (C), and guanine (G) – in a specific sequence to create a chain of nucleotides. By controlling the order in which these nucleic acids are added, researchers can design oligos with precise sequences tailored for various applications, such as PCR, gene editing, or gene expression studies. The resulting oligos can be used in a wide range of molecular biology experiments to probe, manipulate, or detect specific DNA or RNA sequences. The ability to custom-design oligos with specific sequences makes them valuable tools in genetics, biotechnology, and biomedical research.

What are the applications of oligonucleotides?

Oligonucleotides, or oligos, have a wide range of applications across various fields. In diagnostics, oligonucleotides are used in DNA probes to detect specific genetic sequences, which can help in diagnosing genetic disorders and infections. They are also essential components in Nucleic Acid Amplification Tests (NAATs) like PCR-based COVID-19 testing, where oligos play a crucial role in amplifying and detecting target genetic material. Beyond diagnostics, oligonucleotides are utilized in research for gene expression studies, gene editing techniques like CRISPR, and as tools for studying protein-DNA interactions. In the pharmaceutical industry, oligos are being developed as therapeutic agents for treating genetic disorders, cancers, and viral infections. Additionally, oligonucleotides have applications in biotechnology for creating synthetic genes, designing new proteins, and developing novel drug delivery systems. Overall, the versatility of oligonucleotides makes them indispensable in various scientific and medical fields.

How do you pronounce the word ‘oligonucleotide’?

The word “oligonucleotide” is pronounced as AH-lee-go-NOO-klee-uh-tide. The emphasis is on the third syllable, “NOO.” It is a term used in the field of molecular biology to refer to a short, single-stranded DNA or RNA molecule typically made up of 10 to 100 nucleotides. The proper pronunciation of scientific terms is important for effective communication in the scientific community.

How is ‘oligonucleotide’ pronounced?

The term “oligonucleotide” is pronounced as uh-lee-go-NOO-klee-uh-tide. It is a compound word made up of the prefix “oligo-” which means “few” or “small,” and “nucleotide,” which refers to the building blocks of nucleic acids such as DNA and RNA. The correct pronunciation of this term is important for effective communication in scientific and medical contexts.

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